To alleviate discomfort while using crutches, there are several strategies one can employ. Firstly, consider investing in padded handgrips or covers. These soft sleeves not only provide cushioning but also reduce friction. Additionally, ensure that the crutches are adjusted to the correct height. When standing upright, the handgrips should ideally be at wrist level with a slight bend in the elbow when gripping. This adjustment can provide optimal support and minimize strain on the hands.